Blog
Visit our dedicated blog for the latest research, insights, and updates.
Contact Clever
Have a question? Fill out the form and we’ll get back to you.
We’re Clever. We make fruit better.
Clever is an award‑winning biotech innovator focused on microbiome‑balancing health ingredients, particularly those derived from fermented superfruits. Leveraging cutting‑edge synthetic biology methods and microbial technologies, Clever aims to develop a new class of health ingredients. Clever’s products modulate the microbiome and target metabolic health opportunities, aiding the body’s gut, brain, skin and cell health.
DOWNLOAD OUR WHITEPAPERThe Modern Health Crisis Is Cellular
More than 90 % of the global population is metabolically unwell. The root of this
crisis isn’t a mystery—science has identified eight core cellular dysfunctions
that drive nearly all chronic disease. But the solution won’t be found in a pill
bottle. These are not drug problems.
They are food problems.
Traditional food interventions are too slow. Diets are unreliable. Supplements under‑deliver. Pharma treats symptoms, not root causes—and often brings side effects. Worse still, modern living has created a hostile environment inside our bodies. Environmental toxins, ultra‑processed food, viral threats, and stress are dismantling our internal balance — especially in the microbiome, our command center for metabolic and immune health.
At the core, we’re facing a silent epidemic of deficiency. Not a lack of calories or a lack of nutrition — but a lack of bioavailable compounds our cells need to function. This deficiency is not benign. It's degrading our health every day—sometimes gradually, sometimes alarmingly fast.
Fermented Superfruits. Microbial Technology. AI‑Designed Intelligence.
Clever is building a new class of health products that go beyond what supplements
and drugs can do. Our approach doesn’t mask symptoms. It targets the root cellular
dysfunctions, using the most powerful bioactive materials nature has to offer—
transformed through breakthrough science.
We start with the world’s best superfruits — nature’s most potent source of polyphenols. Then we apply proprietary fermentation microbes and AI‑guided synthetic biology to biotransform these compounds into precision‑engineered, microbiome‑modulating arrays of phenolic & microbial metabolites, including postbiotics and short‑chain fatty acids.
These aren’t general health boosters. They’re targeted interventions, delivered directly to the colon, designed to reset the body’s internal balance and activate natural pathways of repair and resilience.
We don’t guess. We design.
And consumers won’t have to wait or wonder if it’s working. They’ll feel the difference early and significantly.
Clever is pursuing deep partnerships with global leaders — one global partner per use case—to bring category‑defining products to market. This is not incremental innovation. This is a new blueprint for how the world approaches food, function, and health.
We believe it’s possible for people to feel better, think sharper, move freely, and live with energy — on their terms. And we’re building the platform to make that possible.
Platform‑Driven Innovation for a New Class of Health Products
Clever designs clinically validated, microbiome‑modulating ingredients for a new
class of consumer health products. Our mission is to enable global consumer brands
to launch products that don’t just promise results — they deliver them, with speed,
precision, and proven efficacy.
We take products from lab to label, supporting our brand partners through clinical trials and regulatory approvals, delivering ingredients they can trust—and consumers can feel.
At the core of our strategy is mastery of metabolite delivery through AI & Synbio led fermentation. We engineer arrays of bioactives—including phenolic metabolites, postbiotics, and short‑chain fatty acids—designed to rebalance the microbiome and restore cellular function. The compounds are naturally derived from our superfruit substrates and optimized using proprietary fermentation microbes.
This is the future of nutraceutical product design: AI‑optimized, precision‑formulated, and biologically intelligent.
We believe the most effective health products won’t be synthetic—they’ll be nature amplified by science. That’s why our core platform uses natural, non‑synthetic fermentation microbes, enhanced with cutting‑edge synthetic biology to improve consistency, bioactive complexity, and health outcomes. Synbio is the catalyst; nature is the foundation.
Solving Microbiome Imbalance & Metabolic Dysfunction
We are targeting the upstream drivers of chronic disease. These are not
diseases themselves but **cellular problems** that are generated from:
Many and even combination of the above create downstream **microbiome deficiencies**.
These are the critical bottlenecks in global health — rooted in microbiome imbalance and metabolite deficiency. Clever’s products work by restoring balance at the source: **modulating the microbiome** and enhancing bioavailability of the critical compounds modern diets fail to deliver.
Our initial focus areas are:
We’re not building generalized wellness products—we’re creating **targeted biotic interventions** designed to shift the consumer’s health state measurably and quickly.
Technically, our goal is to unlock the full potential of nature’s most powerful health food—**superfruit**—by overcoming its biggest limitation: bioavailability. Through microbial fermentation and Synbio precision, **We Make Fruit Better** — more potent, more absorbable, and more impactful than ever before.
---
Full-Spectrum Bioactives. Not Extracts. Not Concentrates.
Where most products reduce nature’s complexity into isolated extracts,
Clever does the opposite. Our fermentation platform captures and
biotransforms the entire spectrum of polyphenols and other food compounds into forms the body can absorb and use.
We deliver what extraction technologies can’t:
This opens the door for our customers to position their products not as another “superfood extract,” but as a **next-generation health solution**—where science meets the full power of nature.
Clever’s mission is to enhance the health of society by increasing the potency of fruit polyphenols through fermentation.
Polyphenols are a category of naturally occurring organic compounds found most plentiful in nature. There are greater numbers & richer polyphenol profiles in plants than animal products, more in fruits than vegetables, and more in berries than other fruit.
Polyphenols are important — they have powerful antioxidant, anti‑inflammatory, and antimicrobial properties. Superfruits get their name from their rich (richest) polyphenol profiles. Our bodies naturally metabolize these beneficial compounds into phenolic metabolites. There are about 8,000 different phenolic metabolites and many have direct and specific health benefits. As a group, they serve as key modulators of neuroinflammation and antioxidant pathways, making important contributions to neuroprotection.
10 Superfruit — 10 Nutraceuticals.
This can change the world by creating a sufficient supply of critical phenolic & microbial metabolites and other protective bioactives—a supply that can be economically manufactured and shipped anywhere in the world.
Transforming Supply Chains. Empowering Global Health Brands.
Clever is building a value chain that starts with what others overlook — farm‑loss fruit waste — and ends with clinically validated, microbiome‑modulating health products that redefine consumer expectations.
```We partner with farmers, growers’ associations, and juice manufacturers to turn undervalued or discarded superfruit into revenue rather than environmental waste.
Through fermentation and synthetic biology, we unlock the full bioactive potential of these fruits — creating new economic opportunities from existing agricultural outputs.
For nutraceutical brands and designer‑distributors, Clever offers a differentiated path to category leadership:
Clever and the bio‑processing industry represent a catalyst for circular economy development—transforming agricultural waste streams into high‑value health solutions.
Agriculture generates persistent waste throughout its distribution model. For most of this waste, bio‑processing offers the most viable industrial pathway. Yet bio‑factories require significant upfront investment and need early high‑value projects to justify their establishment.
Superfruits present an exceptional opportunity. Twenty‑five percent of most fruit’s annual harvests become farm loss. The food with the richest polyphenol profiles in nature — becomes toxic GHG‑producing waste that places water tables at risk. Through bio‑processing, we can unlock the value of this fruit.
Visit our dedicated blog for the latest research, insights, and updates.
Have a question? Fill out the form and we’ll get back to you.